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Reported Question / Answer
Q.) A patient who is being treated for temporal lobe epilepsy(complex partial seizures)and who is having recurrent seizures on his chronic regimen of carbamazepine is given phenobarbital as a second drug.However,the seizures increase in frequency.What is the probable reason for the apparent deleterious effect of adding phenobarbital:
1)
Intracerebral bleeding from worsening bone marrow supression
2)
Decreased carbamazepine level
3)
Decreased stability of CNS neuronal membranes
4)
Hypokalemia
5)
NULL
Answer :
2
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