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Antiplatelet therapy with clopidogrel is usually given for patients with stroke,myocardial infraction and peripheral vascular diseases.Proton pump inhibitors are usually administered along with clopidogrel to prevent the risk of increased gastrointestinal erosion and bleeding.The interaction between clopidogrel and PPI has recently been given much attention due to its clinical significance.Which of the following enzymes is the common pathway of metabolism of both drugs that plays an important role in their interaction.
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